Selected Publications
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CRISPR-Cas enzymes: The toolkit revolutionizing diagnostics
Verosloff MS, Shapiro SJ, Hawkins EM, et al. Biotechnol J . 2021 Sep 10;e2100304. doi: 10.1002/biot.202100304.Learn More -
CRISPR–Cas12-based detection of SARS-CoV-2
Broughton JP, Deng X, Yu G. et al.Learn More
Nat Biotechnology. 2020; doi:10.1038/s41587-020-0513-4 -
Massively parallel kinetic profiling of natural and engineered CRISPR nucleases.
Jones SK, Hawkins JA, Johnson NV, Jung C, Hu K, Rybarski JR, Chen JS, Doudna JA, Press WH, Finkelstein IJ. https://www.biorxiv.org/content/10.1101/696393v1.Learn More -
Candidate Phyla Radiation Roizmanbacteria From Hot Springs Have Novel and Unexpectedly Abundant CRISPR-Cas Systems.
Chen LX, Al-Shayeb B, Méheust R, Li WJ, Doudna JA, Banfield JF. Front Microbiol. 2019;10:928. Published 2019 May 3. doi:10.3389/fmicb.2019.00928Learn More -
Deciphering Off-Target Effects in CRISPR-Cas9 through Accelerated Molecular Dynamics.
Ricci CG, Chen JS, Miao Y, et al. ACS Cent Sci. 2019;5(4):651–662. doi:10.1021/acscentsci.9b00020Learn More -
A Functional Mini-Integrase in a Two-Protein-type V-C CRISPR System.
Wright AV, Wang JY, Burstein D, et al. Mol Cell. 2019;73(4):727–737.e3. doi:10.1016/j.molcel.2018.12.015Learn More -
CasX enzymes comprise a distinct family of RNA-guided genome editors.
Liu JJ, Orlova N, Oakes BL, et al. Nature. 2019;566(7743):218–223. doi:10.1038/s41586-019-0908-x. [published correction appears in Nature. 2019 Apr;568(7752):E8-E10].Learn More -
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes.
Harrington LB, Burstein D, Chen JS, et al. Science. 2018;362(6416):839–842. doi:10.1126/science.aav4294Learn More -
Cutting-Edge Infectious Disease Diagnostics with CRISPR.
Chiu C. Cell Host Microbe. 2018;23(6):702–704. doi:10.1016/j.chom.2018.05.016Learn More -