• Therapeutics
  • Protein Discovery
  • Technologies
  • Diagnostics
  • Partner

  • Resources

    Reading and writing the code of life

    • Publications

      Learn more about our technology

    • Newsroom

      Keep up with our latest news

  • Company

    Reading and writing the code of life

    • About

      Learn more about us

    • Careers

      We’re hiring!

    • Contact

      Get in touch with us

  • We’re hiring

Selected Publications

  • All
  • Diagnostics
  • Therapeutics
  • Protein Discovery
  • Enhanced proofreading governs CRISPR-Cas9 targeting accuracy.

    Chen JS, Dagdas YS, Kleinstiver BP, et al. Nature. 2017;550(7676):407–410. doi:10.1038/nature24268
    Learn More
  • The chemistry of Cas9 and its CRISPR colleagues.

    Chen, J., Doudna, J. Nat Rev Chem 1, 0078 (2017). https://doi.org/10.1038/s41570-017-0078
    Learn More
  • A Broad-Spectrum Inhibitor of CRISPR-Cas9.

    Harrington LB, Doxzen KW, Ma E, et al. Cell. 2017;170(6):1224–1233.e15. doi:10.1016/j.cell.2017.07.037
    Learn More
  • A conformational checkpoint between DNA binding and cleavage by CRISPR-Cas9.

    Dagdas YS, Chen JS, Sternberg SH, Doudna JA, Yildiz A. Sci Adv. 2017;3(8):eaao0027. Published 2017 Aug 4. doi:10.1126/sciadv.aao0027.
    Learn More
  • New CRISPR-Cas systems from uncultivated microbes.

    Burstein D, Harrington LB, Strutt SC, et al. Nature. 2017;542(7640):237–241. doi:10.1038/nature21059
    Learn More
  • Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.

    East-Seletsky A, O'Connell MR, Knight SC, et al. Nature. 2016;538(7624):270–273. doi:10.1038/nature19802
    Learn More
  • CRISPR Immunological Memory Requires a Host Factor for Specificity.

    Nuñez JK, Bai L, Harrington LB, Hinder TL, Doudna JA. Mol Cell. 2016;62(6):824–833. doi:10.1016/j.molcel.2016.04.027
    Learn More
  • Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering.

    Nuñez JK, Harrington LB, Doudna JA. ACS Chem Biol. 2016;11(3):681–688. doi:10.1021/acschembio.5b01019
    Learn More
  • Structures of a CRISPR-Cas9 R-loop complex primed for DNA cleavage.

    Jiang F, Taylor DW, Chen JS, et al. Science. 2016;351(6275):867–871. doi:10.1126/science.aad8282
    Learn More
  • Posts navigation

    Prev 1 2 3 Next

Mammoth Biosciences, Inc.
1000 Marina Blvd.
Brisbane, CA 94005

info@mammothbiosci.com © 2024 Mammoth Biosciences, Inc. | Privacy Policy | Terms of Use