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Diagnostics

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  • CRISPR-Cas enzymes: The toolkit revolutionizing diagnostics

    Verosloff MS, Shapiro SJ, Hawkins EM, et al. Biotechnol J . 2021 Sep 10;e2100304. doi: 10.1002/biot.202100304.
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  • CRISPR–Cas12-based detection of SARS-CoV-2

    Broughton JP, Deng X, Yu G. et al.
    Nat Biotechnology. 2020; doi:10.1038/s41587-020-0513-4
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  • Cutting-Edge Infectious Disease Diagnostics with CRISPR.

    Chiu C. Cell Host Microbe. 2018;23(6):702–704. doi:10.1016/j.chom.2018.05.016
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  • CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.

    Chen JS, Ma E, Harrington LB, et al. Science. 2018;360(6387):436–439. doi:10.1126/science.aar6245
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  • Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.

    East-Seletsky A, O'Connell MR, Knight SC, et al. Nature. 2016;538(7624):270–273. doi:10.1038/nature19802
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