Diagnostics
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CRISPR-Cas enzymes: The toolkit revolutionizing diagnostics
Verosloff MS, Shapiro SJ, Hawkins EM, et al. Biotechnol J . 2021 Sep 10;e2100304. doi: 10.1002/biot.202100304.Learn More -
CRISPR–Cas12-based detection of SARS-CoV-2
Broughton JP, Deng X, Yu G. et al.Learn More
Nat Biotechnology. 2020; doi:10.1038/s41587-020-0513-4 -
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
Chen JS, Ma E, Harrington LB, et al. Science. 2018;360(6387):436–439. doi:10.1126/science.aar6245Learn More -
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection.
East-Seletsky A, O'Connell MR, Knight SC, et al. Nature. 2016;538(7624):270–273. doi:10.1038/nature19802Learn More -